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We use cookies to provide you with a better experience. You can read our Cookie Policy here. Credit: Qing Liu, Nanjing University Read time: window. The study, published in Stem Cell Reports, also identifies a signaling pathway ho a potential target for hearing restoration. Sound waves are collected by the pinna no birth control the outer ear and contrrol funneled into the no birth control canal until they meet the ear drum (tympanic membrane), causing it to vibrate.

Movement of the bones transmits the sound no birth control to the inner ear, sending a signal to the cochlea (a hollow cabinet structure filled with fluid).

Vibrations cause the fluid within the cochlea to ripple, forming waves that nk the movement of hair cells positioned on the top of the basilar membrane that separates the two fluid-filled chambers running along the cochlea.

Structure of the human ear. Hair today, gone tomorrowHearing loss affects more than 300 million people across the globe and can be caused by a variety of factors. Birthh high-throughput screen identified an anti-cancer drug called regorafenib that could do just that. It works by suppressing the formation biryh new blood vessels required by tumors. Interestingly, in our study, regorafenib promotes hair cell regeneration in a different mechanism, whereby it inhibits the production of an anti-differentiation molecule TGFB1.

Until now, according to Wan, no birth control key no birth control to the large-scale screening of modulators for hair cell regeneration np the lack of a high-throughput mammalian hair cell culture platform.

As for regorafenib, the researchers are currently investigating its hair cell-inducing effects in vivo in preclinical rodent models. Reference: Lui Q, Zhang L, Zhu M-S, Wan G. High-throughput screening on cochlear organoids identifies VEGFR-MEKTGFB1 signaling promoting hair cell reprogramming. Credit: Qing Liu, No birth control University Read time: A research no birth control from Nanjing University has used cochlear organoids to identify drugs that can promote the regeneration of hair cells.

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