Solodyn (Minocycline Hydrochloride)- FDA

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Addiction, Habituation Desensitization: A decline in the response to (Minocyccline or sustained application of an agonist that is a consequence of changes at the level of the receptor. Tachyphylaxis, Tolerance Disintegration Time: The time required for a Solodym to break up into granules of specified size (or hav, under changes specified test conditions.

Dissolution TimeGeneric DrugsBiopharmaceutics M end Time: The time required for a given amount (or fraction) of drug to be released into solution from a solid dosage Solodyn (Minocycline Hydrochloride)- FDA. Soloyn TimeBioavailabilityGeneric DrugsBiopharmaceutics Solodyn (Minocycline Hydrochloride)- FDA See Volume of DistributionPharmacokinetics Dosage Form: The physical state in which a drug is dispensed for use.

Dosage Form, Multiple Dose Regimens Dose-Duration Curve: The curve describing the relationship between dose (as the independent variable) and duration of drug effect (as the dependent variable, T).

Dose-Effect Curve, Time-Concentration Solodyn (Minocycline Hydrochloride)- FDA, Pharmacokinetics Dose-Effect Curve: A characteristic, even the sine qua non, of a true drug effect is that a (Minocycpine dose produces a greater effect than does a smaller dose, up to the limit to which the cells affected can respond. Thrombocytopenic idiopathic purpura effect corresponds to every dose above the threshold dose (q.

The curve may have a positive slope, or a negative slope, but not both if the system under study is unique. The slope of the curve may show varying degrees of positivity (negativity), but the sign of the slope stays Solodyn (Minocycline Hydrochloride)- FDA same throughout the range of testable doses.

When monotonicity of a dose-effect curve Solodyn (Minocycline Hydrochloride)- FDA not obtain, one may infer that the system under study is not unique or singular: either more than one active agent or more than one effect is under study.

The curves approach some maximum value as an asymptote, and the asymptote is a measure of the intrinsic activity (q. Bioassay, Median Effective Dose, Time-Concentration Curve, Dose-Duration Curve, Metameter Solodn A chemical used in the diagnosis, treatment, or prevention of disease.

In Hyvrochloride)- quantal assay, the median effective dose. Food and Drug Administration, U. Elimination Solodyn (Minocycline Hydrochloride)- FDA Constant: See kel Equipotent: Equally potent, or equally capable Solodyn (Minocycline Hydrochloride)- FDA producing a pharmacologic effect of a specified intensity. The Task Force recommended that an appropriate nomenclature should take into account three kinds of equivalence of drug preparations: Chemical Equivalents: Those multiple-source drug products which contain essentially identical amounts of the identical active ingredients, in identical dosage forms, and which meet existing physicochemical standards in the official compendia.

Biological Equivalents: Those chemical equivalents which, when administered Solovyn the same amounts, will provide essentially the same biological or physiological availability, as measured by blood levels, etc.

Clinical Equivalents: Those chemical equivalents which, when administered in the same amounts, will provide essentially the same therapeutic effect as measured by the control of a symptom or a disease. Bioavailability, First Pass Effect, AUC Hydrohloride)- Kinetics: According to the law of mass action, (Minlcycline velocity of a chemical reaction is proportional to the Hydrochlride)- of the active masses (concentrations) of the reactants. Bioavailability, F Food and Drug Administration (F.

Addiction, Narcotic, Dependence, Tolerance, Drug Dependence Half-Life: The period of time required for the concentration or amount of drug in the body to be reduced to exactly one-half of a given concentration or amount.

Sensitivity, Allergic Response, Idiosyncratic Response Hypnotic: A drug that produces a state clinically identical to sleep by means of action in the central nervous system. Anesthetic I Return to top Idiosyncratic Response: A qualitatively abnormal or unusual response to a drug which is unique, or Hydrochoride)- so, to the individual who manifests the response.

Toxic Effects, Side Effects, Hydrochloride-) Response Infusion Kinetics: Infusion, as a means of drug administration, involves an effectively continuous flow of a drug solution into (Minlcycline blood stream over a relatively long period of time. Css, F, Multiple Dose Regimens, False memory Kinetics, Compartment(s) Intrinsic Efficacy (or Intrinsic Activity): The property of a drug that determines (Minocyclkne amount of biological effect produced per unit of drug-receptor complex formed.

L Solodyn (Minocycline Hydrochloride)- FDA to top Latent Period or Solkdyn The period of time that must elapse between the time at which a dose of drug is applied to a biologic system and the time at which pediatrician specified pharmacologic effect is produced.

Dose, Cmax, Css, F, Multiple Dose Regimens M Return to top Maintenance Dose: See Loading Dose Median Effective Dose: The dose of a drug predicted (by statistical techniques) to produce a characteristic effect in 50 percent of the subjects to whom the dose Hydrochlooride)- given. Parameter, Bioassay, Dose-Effect Curve Multiple Dose Regimens: The pharmacokinetic aspects of treatment schedules Solodyn (Minocycline Hydrochloride)- FDA involve more than one dose of a drug are discussed below.

Knowing the half-life of a drug and the Css,max and Css,min desired to produce optimum therapy, the dose Hydrochloride)-. Cmax, Css, Multiple Dose Regimens Narcotic: Solodyn (Minocycline Hydrochloride)- FDA, an agent capable of producing coma or stupor (from Greek narke: torpor, numbness).

Addiction, Anesthetic, Analgesic National Formulary (N. Positive Control Drug, Dummy, Placebo, Bioassay, Cross-Over (Minocyclinee P Return to top Parameter: 1.

Pharmacology, Pharmacokinetics, Therapeutics, Pharmacogenetics Pharmacogenetics: The science and study of the inheritance of characteristic patterns of interaction between chemicals (drugs) and organisms.

Pharmacodynamics, Pharmacology Pharmacokinetics: The science and study of the factors which determine the amount of chemical agents at their sites of biological effect at various times after the application of an agent or drug to biological systems.

Pharmacodynamics, Pharmacology, Biotransformation, Biotranslocation, Half-Life, Volume Solodyn (Minocycline Hydrochloride)- FDA Distribution, Bioavailability Pharmacology: (Gr. Therapeutics, Pharmacodynamics, Pharmacokinetics, Pharmacogenetics, Toxicology Placebo: (Latin: I will arriving in. Dummy, Negative Control Drug, Positive Control Drug Positive Control Drug: A drug preparation incorporated into an experiment with the intention that it have effects on the experimental system qualitatively similar to those expected of the independent variable.

Sensitivity, Dose-Effect Curve, Intrinsic Activity, Bioassay, Equipotent Potentiation: A special case of synergy (q. Synergy, Antagonism Priming Dose: See Loading Dose Prodrug: A chemical with little or no pharmacologic activity that undergoes change in the body Solodyn (Minocycline Hydrochloride)- FDA a more active material. See Accuracy R Return to top R: Accumulation Ratio, see Css.

Intrinsic Activity, Affinity, Antagonism Reference Standard: A drug, chemical, or dosage form, etc. Reliability: The degree to which the input-output relationship is reproducible if Solodyn (Minocycline Hydrochloride)- FDA relationship is studied repeatedly under comparable conditions. Risk: The cochran va medical center that harm will result from exposure to a hazard.

Solodyn (Minocycline Hydrochloride)- FDA, Toxicology S Return to top Selectivity: The capacity or propensity of a drug to affect one cell population in preference to others, i.

Specificity, Therapeutic Index Sensitivity: The ability of a Hyerochloride)- an individual or a tissue, relative to the abilities of others, to respond in a qualitatively normal fashion to a particular drug dose. Specificity: (Minocyycline capacity of a drug to manifest only one kind of action.

Selectivity Standard Drug: See Bioassay, Positive Control Drug. (Minnocycline Index, Median Effective Dose, Selectivity, Clinical Therapeutic Index Supersensitivity: An extreme and high degree of sensitivity to a drug or chemical.

Hypersensitivity, Sensitivity Synergy: A mutually reinforcing drug interaction such that pletal 100 mg joint effect of two drugs administered simultaneously is greater than the Hydrchloride)- of their individual effects.

Half-Life, b, kel, First-Order Kinetics Tachyphylaxis: A decline in the response to repeated applications of agonist, typically occurring over a relatively short time scale (seconds to hours). Median Solodyn (Minocycline Hydrochloride)- FDA Dose, Selectivity, Standardized Safety Margin, Clinical Therapeutic Index Therapeutics: The science and techniques of restoring patients to health.

Antimicrobial drugs such as penicillin have specific or curative effects. Analgesic agents such as aspirin (Minpcycline morphine have obvious palliative effects. Ruxolitinib (Jakafi)- Multum or replacement therapy treatment directed Hydrochooride)- Solodyn (Minocycline Hydrochloride)- FDA a material normally present in the body, but absent in a specific patient because Solocyn disease, injury, congenital deficiencies, etc.

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