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Natural Medicines Comprehensive Database rates effectiveness based on scientific evidence according to the following scale: Effective, Likely Effective, Possibly Effective, Possibly Ineffective, Likely Ineffective, and Insufficient Evidence to Rate (detailed description of each of the ratings). The progesterone prescription products that have been approved by the Food and Drug Administration (FDA) are LIKELY SAFE for most people when used by mouth, applied to the skin, applied into vagina, or injected into the muscle with the advice and care of a healthcare professional.

There is not enough reliable information about the safety of taking progesterone if you are breast-feeding. Injecting high-doses of progesterone intravenously (by IV) in combination with the drug paclitaxel might increase levels of paclitaxel in the blood.

However, the combination does not seem to increase the side effects of paclitaxel. Until more is known, use progesterone cautiously or avoid using in patients being treated with paclitaxel. BY MOUTH: For hormone replacement therapy: 200 mg micronized progesterone (Prometrium) per day is typically taken for 12 days of a 25-day cycle with 0.

INSIDE THE VAGINA: For breast pain associated with noncancerous breast disease: a typical dose of 4 grams of vaginal cream containing 2. For reducing vaginal bleeding and reversing the thickening of the lining of the uterus in premenopausal women with noncancerous endometrial hyperplasia: a dose of 100 mg progesterone cream placed inside the vagina daily from day 10 to day 25 of a 28-day cycle has been used.

Effects of sex steroids on protein synthesis in cultured human lymphocytes. Hormonal aspects of postpartum depression. Does male sexual behavior require progesterone. Microarray profiling of gene expression patterns in adult male rat brain following acute progesterone treatment. Correlation of symptoms in pre-menstrual tension to oestrogen and progesterone concentrations in blood plasma. Electrophysiological and psychological changes induced by steroid hormones in men and women.

Bicakci S, Uysal H Sarica Y Giray S Demirkiran M Bicakci K. Ischemic infarct - due to basilary migraine. Neurosteroid secretion in panic disorder. Etiology and treatment of menstrual disorders. Progesterone, estradiol, testosterone and dihydrotestosterone: effects on rate of extinction of a conditioned taste aversion in rats. The number of pregnancies is a risk factor for Alzheimer's disease. Interhemispheric integration during the menstrual cycle: failure to confirm progesterone-mediated interhemispheric decoupling.

Salience of emotional displays of danger and contagion in faces is enhanced when progesterone levels are raised. Endocrine regulation of HOX genes. Daitzman, Reid and Zuckerman, Marvin. Disinhibitory sensation seeking, personality and gonadal hormones. Associations between circulating sex steroid hormones and cognition in normal elderly women. Ovarian hormones and binge eating in bulimia nervosa. Yasli Kadin ve Erkeklerde Depresi f Duygudurum ve Endojen Seks Hormonlari Arasindaki I li ki.

Serum levels of androgens are higher in women with premenstrual irritability and dysphoria than in controls. Menstrual cycle-dependent neural plasticity in the adult human brain is hormone, task, and region specific.

Regulation of cholesterol metabolism in the intestine. A new look at the 5alpha-reductase inhibitor finasteride. Parental reproductive problems and gestational hormonal exposure in autistic and schizophrenic children. Assessment of cognitive performance after progesterone administration in healthy male volunteers. Premenstrual changes and changes in gonadal hormones.

Increased neuroactive steroid concentrations in women with bipolar disorder or major depressive disorder. The hormonal environment of post-natal depression. Cardiff puerperal mood and hormone study. Postnatal depression at 5 to 6 weeks postpartum, and its hormonal correlates across the peripartum period. Der Einfluss von Sexualhormonen auf funktionelle cerebrale Asymmetrien.

Postpartum blues: relationship between not-protein bound steroid hormones in plasma and postpartum mood changes. Human sleep patterns after progesterone administration. Are disturbances in lipid-protein interactions by phospholipase-A2 a predisposing factor in affective illness. Perceptual--motor performance during the menstrual cycle. Ingram JC, Greenwood RJ Woolridge MW.